Chiller & Cooling Best Practices, May 2017, by Fred Berry.
http://www.coolingbestpractices.com/technology/chillers/vsd-chillers-deliver-energy-savings-under-real-world-operation

"Manufacturers are under continual pressure to control costs without affecting operations or worker comfort and safety. Because energy ranks as one of the largest operating expenses, improving energy efficiency of mechanical cooling systems is one of the best ways to reduce operating costs. In a typical water-cooled chiller plant, the chiller itself accounts for most of the energy consumption. That’s why improving chiller efficiency is critical to controlling operating costs."